Mobility Measurements Probe Conformational Changes in Membrane Proteins due to Tension
نویسندگان
چکیده
منابع مشابه
Mobility Measurements Probe Conformational Changes in Membrane Proteins due to Tension.
The function of membrane-embedded proteins such as ion channels depends crucially on their conformation. We demonstrate how conformational changes in asymmetric membrane proteins may be inferred from measurements of their diffusion. Such proteins cause local deformations in the membrane, which induce an extra hydrodynamic drag on the protein. Using membrane tension to control the magnitude of t...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2015
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.115.198101